The corona virus disease (COVID-19) was declared a pandemic in March 2020 by the World Health organization. As of September 2022, more than 618,000,000 people have been identified to have contracted the infection and more than 6,500,000 associated deaths have been confirmed globally. The intensity and the spread of the disease over time in various countries and regions has been determined primarily by the management strategies adopted however several populations have had an increased likelihood of exposure across the globe. The goal of this paper is to identify environmental factors that may increase the likelihood of a population at risk for contracting the disease. Several environmental factors can heighten the vulnerability of populations to the disease causing them to have a higher risk for both contracting and spreading the disease within their population. The paper highlights the urgent need to manage these environmental triggers that result in inequalities across the globe when facing health crisis situations.